Symptoms of comorbid disorders are common among psychostimulant users, as they are among other types of drug users. The most commonly documented comorbid conditions are drug-induced psychosis, depression and anxiety. Well-validated screening, diagnostic instruments and symptom checklists are available and their use is strongly recommended.

Overall, there is a paucity of research on the effectiveness of diagnosing and treating comorbid conditions among psychostimulant users and few well-controlled evaluations of specific interventions for comorbid conditions among psychostimulant users per se. Consequently, it is not possible to recommend any specific interventions for comorbid conditions at this point, although a general recommendation would be to encourage diagnosis and integrated treatment of comorbid conditions among psychostimulant users.