Better health and ageing for all Australians

Pharmaceutical Benefits Advisory Committee

Glossary of Q Terms

Glossary to accompany the November 1995 edition of the Guidelines for the Pharmaceutical Industry on Preparation of Submissions to the Pharmaceutical Benefits Advisory Committee

Q-TWiST
quality-adjusted time without symptoms and toxicity 
QALY
quality-adjusted life-year
Quality of life (see also health status)
The extent to which an individual perceives himself or herself able to function physically, psychologically and socially.
Quality-adjusted life-year (see also healthy-year equivalent)
The number of years of life weighted by a utility value of the relative quality of life experienced.  
Quality-adjusted time without symptoms and toxicity
A method of estimating quality-adjusted life-years (developed originally in cancer research) which divides life expectancy into: time with toxicity from chemotherapy; followed by time free of symptoms of disease or chemotherapy toxicity; followed by time with disease symptoms. Each of these time periods is adjusted by the respective utility weight.  
Quasi-experimental study (see Appendix N)
A non-randomised study in which the investigator lacks full control over the allocation and/or the timing of the therapy, but otherwise conducts the study as a randomised trial. An umbrella term for "before and after" studies, case series with historical controls and comparison of the results of single-arm studies.