Better health and ageing for all Australians

Departmental Speeches

Australian Health Management Plan for Pandemic Influenza

Presentation by Professor John Horvath, Chief Medical Officer, to the Allfinance BCP/DR Forum in Brisbane on 28 August 2006.

In this section:

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28 August 2006

Slide 1

Australian Health Management Plan for Pandemic Influenza, Allfinance BCP/DR Forum, Brisbane, 28 August 2006

Slide 2

Pandemics have been documented since 1889, occurring in 10-40 year cycles. Historical anecdotes date pandemic like events as far back as 1100’s, some catastrophic.

Slide 3

Deaths
1918-19Spanish Influenza20-50 million
1957Asian Influenzaapprox. 1 million
1968-9Hong Kong Influenzaapprox. 1 million

Slide 4

[image: Areas reporting confirmed cases of H5N1 avian influenza in poultry and wild birds since 2003 - status as of 14 August 2006]

Slide 5: Confirmed human cases

Indonesia

  • Cases: 60
  • Deaths: 46

Vietnam

  • Cases: 93
  • Deaths: 42

Thailand

  • Cases: 24
  • Deaths: 16

China

  • Cases: 21
  • Deaths: 14

Egypt

  • Cases: 14
  • Deaths: 6

Cambodia

  • Cases: 6
  • Deaths: 6

Azerbaijan

  • Cases: 8
  • Deaths: 5

Turkey

  • Cases: 12
  • Deaths: 4

Iraq

  • Cases: 2
  • Deaths: 2

Djibouti

  • Cases: 1
  • Deaths: 0
Of the 241 human cases reported, more than half have resulted in death.

Slide 6

[image: Affected areas with confirmed human cases of H5N1 avian influeza since 2003 - status as of 14 August 2006 ]

Slide 7: Indonesia - Sumatran Cluster May 2006

  • 8 cases in family cluster- 7 deaths.
  • Index case - exposed to sick chickens? Onset illness 27th April
  • Case 2- 7 onset 3-6th May, Case 8 onset 12 May - suggestive of chains of infection
  • No H5N1 identified in animals or environment
  • WHO statement - likely human to human transmission cannot exclude environmental source
  • Key viral genetic sequences remain the same

Slide 8: Impact of pandemic strain in Australia

In Australia's population with an attack rate of 25% we would expect over 6-8 weeks:
  • 13,000 deaths (2,000 children, 7,000 elderly)
  • 57,900 hospitalisations
  • 2.6 million outpatient visits
  • Workplace absenteeism 30-50%

Source: Meltzer CDC 2003

Slide 9

PeriodWHO PhaseAustralian PhaseDescription of Phase
Inter-pandemicAus 0No animal disease in Australia
1OS 1Animal infection overseas: low human risk
Aus 1Animal infection Australia: low human risk
2OS 2Animal infection overseas: high human risk
Aus 2Animal infection Australia: high human risk
Pandemic alert3OS 3Human infection overseas with new subtype(s): no human-to-human spread
Aus 3Human infection in Australia with new subtype(s): no human-to-human spread
4OS 4Human infection overseas- small cluster(s), limited human-to-human transmission
Aus 4Human infection in Australia- small cluster(s), limited human-to-human transmission
5OS 5Human infection overseas- larger cluster(s), substantial pandemic risk
Aus 5Human infection in Australia- larger cluster(s), substantial pandemic risk
Pandemic6OS 6Pandemic overseas- not in Australia: increased and sustained transmission in general population
Aus 6aPandemic in Australia- localised (one area of country)
Aus 6bPandemic in Australia- widespread (multiple areas)
Aus 6cPandemic in Australia- subsided
Aus 6dPandemic in Australia- next wave

Slide 10: What has Australia done to prepare?


Slide 11: Preparedness 2003-2006

Department of Health

  • The National Incident Room upgraded
  • Office of Health Protection
  • High level representation on peak committees
  • Scenario testing - Exercise Cumpston

Border

  • Training for border workers
  • Thermal scanners purchased
  • Development of border protocols
  • International Aid

Slide 12: Preparedness 2003-2006

Surveillance

  • Development of rapid on line surveillance and case management tools
  • Secure networks

Laboratory

  • Upgrading of public health laboratory capacity
  • Relocation and upgrading of the WHO Collaborating Centre for influenza

Slide 13: Preparedness 2003-2006

Vaccines

  • Two contracts, on soil and overseas

  • Pandemic capacity plus research and development

  • Recent additional funding to CSL Ltd:

    • fast track clinical trials (finalise Sept 06)

    • immediate and potential stockpile pandemic vaccine capacity

Slide 14: Preparedness 2003-2006

Stockpile $342.7m

  • Anitvirals
  • Additional antibiotics
  • Infection Control Equipment (masks, gloves)
  • Vaccination Packs
  • Negative Pressure Units
  • Quarantine Caches

Slide 15: Preparedness 2003-2006

  • Establishment of The Office of Health Protection
  • Communications Strategy
  • Review of Urgent Research Needs
  • Australian Management Plan for Pandemic Influenza - June 2006, revised May 2006
  • International Support $141m

Slide 16: What will we do if it happens?


Slide 17: Modelling

  • Papers by Ferguson et al, Longini et al indicate a pandemic may be stopped by use of antivirals and quarantine*
  • Modelling currently being carried out in Australia indicates home quarantine and social distancing can have a major effect in 'blunting' epidemiological curve

* Ferguson NM, Cummings DA et al. Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature. Vol 437/8 September 2005. 209 - 214

Longini IM, Azhar Nizam et al. Containing Pandemic Influenza at the Source. Science Vol 309 12 August 2005. 1083-1085


Slide 18

[Graph: Pandemic Influenza Cases in Sydney 1919]

Slide 19

[Graph: Personal infection control and distancing]

Slide 20

[Graph: Quarantining households]

Slide 21

[Graph: Effect of combining interventions on delay]

Slide 22: Containment

Keeping it out

Border control

  • screening to closure

Antiviral policy

  • for prophylaxis

Use of quarantine

  • home quarantine
  • Consideration of mass quarantine in Overseas 5 and 6

Slide 23: Border control options

CurrentPositive Pratique
Pratique by exceptionScreening of select arrivals:
  • declaration forms;
  • thermal scanning
  • nurse assessment
  • isolation and quarantine
Screening baggage for chicken productsScreening all arrivals
Health information sheetDiverting flights from specific locations

Slide 24: Containment

Stamping it out

  • Use of antivirals for prophylaxis
  • Treatment of index case
  • Use of home quarantine
  • Emphasis on early detection (testing)
  • May use internal border controls or 'ring fencing'

Slide 25: Maintenance of social function

Keep society functioning

  • Continuous antivirals
    • for health care workers managing cases
  • Post-exposure prophylaxis
    • for those at less risk
  • Treatment if symptomatic
    • depends on effectiveness of antivirals
  • Quarantine
    • Still advised, monitoring to cease
    • Ban on mass gatherings advised to continue

Slide 26: Whole of Government approach: Interdepartmental committees

Prime Minister and Cabinet

  • Food Supply
  • Business Continuity
  • Social Services
  • Economic impact
  • Foreign Policy

Slide 27: Urgent research

  • Symposium in April 2005
    • Confirmed capacity
    • Determined priorities

  • $6.57 million awarded
    • Detection and monitoring (8)
    • Public Health Intervention (5)
    • Antivirals (incl resistance) (3)
    • Pandemic vaccine (9)
    • Behavioural response (4)
    • Other (4)

Slide 28: Thank you.




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