Departmental Speeches
Australian Health Management Plan for Pandemic Influenza
Presentation by Professor John Horvath, Chief Medical Officer, to the Allfinance BCP/DR Forum in Brisbane on 28 August 2006.
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28 August 2006
Slide 1
Australian Health Management Plan for Pandemic Influenza, Allfinance BCP/DR Forum, Brisbane, 28 August 2006Slide 2
Pandemics have been documented since 1889, occurring in 10-40 year cycles. Historical anecdotes date pandemic like events as far back as 1100’s, some catastrophic.Slide 3
| Deaths | ||
| 1918-19 | Spanish Influenza | 20-50 million |
| 1957 | Asian Influenza | approx. 1 million |
| 1968-9 | Hong Kong Influenza | approx. 1 million |
Slide 4
[image: Areas reporting confirmed cases of H5N1 avian influenza in poultry and wild birds since 2003 - status as of 14 August 2006]Slide 5: Confirmed human cases
Indonesia
- Cases: 60
- Deaths: 46
Vietnam
- Cases: 93
- Deaths: 42
Thailand
- Cases: 24
- Deaths: 16
China
- Cases: 21
- Deaths: 14
Egypt
- Cases: 14
- Deaths: 6
Cambodia
- Cases: 6
- Deaths: 6
Azerbaijan
- Cases: 8
- Deaths: 5
Turkey
- Cases: 12
- Deaths: 4
Iraq
- Cases: 2
- Deaths: 2
Djibouti
- Cases: 1
- Deaths: 0
Slide 6
[image: Affected areas with confirmed human cases of H5N1 avian influeza since 2003 - status as of 14 August 2006 ]Slide 7: Indonesia - Sumatran Cluster May 2006
- 8 cases in family cluster- 7 deaths.
- Index case - exposed to sick chickens? Onset illness 27th April
- Case 2- 7 onset 3-6th May, Case 8 onset 12 May - suggestive of chains of infection
- No H5N1 identified in animals or environment
- WHO statement - likely human to human transmission cannot exclude environmental source
- Key viral genetic sequences remain the same
Slide 8: Impact of pandemic strain in Australia
In Australia's population with an attack rate of 25% we would expect over 6-8 weeks:- 13,000 deaths (2,000 children, 7,000 elderly)
- 57,900 hospitalisations
- 2.6 million outpatient visits
- Workplace absenteeism 30-50%
Source: Meltzer CDC 2003
Slide 9
| Period | WHO Phase | Australian Phase | Description of Phase |
| Inter-pandemic | Aus 0 | No animal disease in Australia | |
| 1 | OS 1 | Animal infection overseas: low human risk | |
| Aus 1 | Animal infection Australia: low human risk | ||
| 2 | OS 2 | Animal infection overseas: high human risk | |
| Aus 2 | Animal infection Australia: high human risk | ||
| Pandemic alert | 3 | OS 3 | Human infection overseas with new subtype(s): no human-to-human spread |
| Aus 3 | Human infection in Australia with new subtype(s): no human-to-human spread | ||
| 4 | OS 4 | Human infection overseas- small cluster(s), limited human-to-human transmission | |
| Aus 4 | Human infection in Australia- small cluster(s), limited human-to-human transmission | ||
| 5 | OS 5 | Human infection overseas- larger cluster(s), substantial pandemic risk | |
| Aus 5 | Human infection in Australia- larger cluster(s), substantial pandemic risk | ||
| Pandemic | 6 | OS 6 | Pandemic overseas- not in Australia: increased and sustained transmission in general population |
| Aus 6a | Pandemic in Australia- localised (one area of country) | ||
| Aus 6b | Pandemic in Australia- widespread (multiple areas) | ||
| Aus 6c | Pandemic in Australia- subsided | ||
| Aus 6d | Pandemic in Australia- next wave |
Slide 10: What has Australia done to prepare?
Slide 11: Preparedness 2003-2006
Department of Health
- The National Incident Room upgraded
- Office of Health Protection
- High level representation on peak committees
- Scenario testing - Exercise Cumpston
Border
- Training for border workers
- Thermal scanners purchased
- Development of border protocols
- International Aid
Slide 12: Preparedness 2003-2006
Surveillance
- Development of rapid on line surveillance and case management tools
- Secure networks
Laboratory
- Upgrading of public health laboratory capacity
- Relocation and upgrading of the WHO Collaborating Centre for influenza
Slide 13: Preparedness 2003-2006
Vaccines
- Two contracts, on soil and overseas
- Pandemic capacity plus research and development
- Recent additional funding to CSL Ltd:
- fast track clinical trials (finalise Sept 06)
- immediate and potential stockpile pandemic vaccine capacity
Slide 14: Preparedness 2003-2006
Stockpile $342.7m
- Anitvirals
- Additional antibiotics
- Infection Control Equipment (masks, gloves)
- Vaccination Packs
- Negative Pressure Units
- Quarantine Caches
Slide 15: Preparedness 2003-2006
- Establishment of The Office of Health Protection
- Communications Strategy
- Review of Urgent Research Needs
- Australian Management Plan for Pandemic Influenza - June 2006, revised May 2006
- International Support $141m
Slide 16: What will we do if it happens?
Slide 17: Modelling
- Papers by Ferguson et al, Longini et al indicate a pandemic may be stopped by use of antivirals and quarantine*
- Modelling currently being carried out in Australia indicates home quarantine and social distancing can have a major effect in 'blunting' epidemiological curve
* Ferguson NM, Cummings DA et al. Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature. Vol 437/8 September 2005. 209 - 214
Longini IM, Azhar Nizam et al. Containing Pandemic Influenza at the Source. Science Vol 309 12 August 2005. 1083-1085
Slide 18
[Graph: Pandemic Influenza Cases in Sydney 1919]Slide 19
[Graph: Personal infection control and distancing]Slide 20
[Graph: Quarantining households]Slide 21
[Graph: Effect of combining interventions on delay]Slide 22: Containment
Keeping it out
Border control
- screening to closure
Antiviral policy
- for prophylaxis
Use of quarantine
- home quarantine
- Consideration of mass quarantine in Overseas 5 and 6
Slide 23: Border control options
| Current | Positive Pratique |
| Pratique by exception | Screening of select arrivals:
|
| Screening baggage for chicken products | Screening all arrivals |
| Health information sheet | Diverting flights from specific locations |
Slide 24: Containment
Stamping it out
- Use of antivirals for prophylaxis
- Treatment of index case
- Use of home quarantine
- Emphasis on early detection (testing)
- May use internal border controls or 'ring fencing'
Slide 25: Maintenance of social function
Keep society functioning
- Continuous antivirals
- for health care workers managing cases
- Post-exposure prophylaxis
- for those at less risk
- Treatment if symptomatic
- depends on effectiveness of antivirals
- Quarantine
- Still advised, monitoring to cease
- Ban on mass gatherings advised to continue
Slide 26: Whole of Government approach: Interdepartmental committees
Prime Minister and Cabinet
- Food Supply
- Business Continuity
- Social Services
- Economic impact
- Foreign Policy
Slide 27: Urgent research
- Symposium in April 2005
- Confirmed capacity
- Determined priorities
- $6.57 million awarded
- Detection and monitoring (8)
- Public Health Intervention (5)
- Antivirals (incl resistance) (3)
- Pandemic vaccine (9)
- Behavioural response (4)
- Other (4)
Slide 28: Thank you.
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