Australian national notifiable diseases case definitions
Rubella case definition
This document contains the case definitions for rubella which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.
Communicable Diseases Surveillance
Australian national notifiable diseases case definitions - Rubella
ReportingBoth confirmed cases AND probable cases should be notified.
Confirmed caseA confirmed case requires Laboratory definitive evidence only.
Laboratory definitive evidence1. Isolation of rubella virus
2. Detection of rubella virus by nucleic acid testing
3. IgG seroconversion or a significant increase in antibody level or a fourfold or greater rise in titre to rubella virus in the absence of recent rubella vaccination. The results must be established by the testing of paired sera in parallel.
4. Detection of rubella-specific IgM, in the absence of recent rubella vaccination. (Note that in pregnant women, the result needs to be confirmed in a reference laboratory.)
Probable caseA probable case requires:
1. clinical evidence
2. Laboratory suggestive evidence OR epidemiological evidence.
Laboratory suggestive evidenceIn a pregnant patient, detection of rubella-specific IgM that has not been confirmed in a reference laboratory, in the absence of recent rubella vaccination.
Clinical evidence1. A generalised maculopapular rash
3. arthralgia/arthritis OR lymphadenopathy OR conjunctivitis.
Epidemiological evidenceAn epidemiological link is established when there is:
1. Contact between two people involving a plausible mode of transmission at a time when:
a) one of them is likely to be infectious (about one week before to at least four days after appearance of rash)
b) the other has an illness which starts within 14 and 23 days after this contact
2. At least one case in the chain of epidemiologically linked cases (which may involve many cases) is laboratory confirmed.