Australian national notifiable diseases case definitions
Q fever case definition
This document contains the case definitions for Q fever which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.
Communicable Diseases Surveillance
Australian national notifiable diseases case definitions - Q fever
Reporting
Only confirmed cases should be notified.Confirmed case
A confirmed case requires either:1. Laboratory definitive evidence
OR
2. Laboratory suggestive evidence AND clinical evidence.
Laboratory definitive evidence
1. Detection of Coxiella burnetii by nucleic acid testingOR
2. Seroconversion or significant increase in antibody level to Phase II antigen in paired sera tested in parallel in absence of recent Q fever vaccination
OR
3. Detection of C. burnetii by culture (note this practice should be strongly discouraged except where appropriate facilities and training exist.)
Laboratory suggestive evidence
Detection of specific IgM in the absence of recent Q fever vaccination.Clinical evidence
A clinically compatible disease.

