Human immunodeficiency virus (HIV) (unspecified) case definition

This document contains the case definitions for Human immunodeficiency virus - unspecified which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.

Page last updated: 12 March 2004

Australian national notifiable diseases case definitions - Human immunodeficiency virus (HIV) - unspecified

HIV infection (unspecified) is diagnosed in individuals aged 18 months or older at the time of blood sample collection, who do not have evidence of HIV acquisition in the previous 12 months. A diagnosis of HIV infection (unspecified) excludes a diagnosis of newly acquired HIV infection.

Reporting

Both confirmed cases and probable cases should be notified.

Confirmed case

A confirmed case requires laboratory definitive evidence only AND that the case does not meet any of the criteria for a newly acquired case.

Laboratory definitive evidence

1. Repeatedly reactive result on a screening test for HIV antibody followed by a positive result on a western blot. A positive result on a western blot is defined by the presence of a glycoprotein band (gp41, gp120 or gp160) and at least three other HIV-specific bands

OR

2. Detection of HIV by at least two virologic assays (nucleic acid testing for proviral DNA; HIV p24 antigen, with neutralisation; virus isolation) performed on at least two separate blood samples.

Probable case

A probable case requires Laboratory suggestive evidence only.

Laboratory suggestive evidence

Detection of HIV by at least one of the following virologic assays (nucleic acid testing for proviral DNA; HIV p24 antigen, with neutralisation; virus isolation) in one blood sample.


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