Hepatitis C (newly acquired) case definition

This document contains the case definitions for Hepatitis C - newly acquired which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.

Page last updated: 25 September 2015

Australian national notifiable diseases case definitions - Hepatitis C (newly acquired)

Version Status Last reviewed Endorsement Date Implementation date
1.1 In ‘Laboratory definitive evidence’ change ‘Detection of hepatitis C virus by nucleic acid testing in a child aged 28 days to 24 months’ TO ‘Detection of hepatitis C virus by nucleic acid testing in a child aged 3 months to 24 months.’

In ‘Laboratory suggestive evidence’ added ‘…in a patient with no prior evidence of hepatitis C infection.’

In ‘Clinical evidence’ changed Alanine transaminase (ALT) from seven to ten times upper limit of normal.

July 2014 3 December 2014 1 January 2015
1.0 Initial CDNA case definition (2004).

Reporting

Only confirmed cases should be notified.

Confirmed case

A confirmed case requires either:

1. Laboratory definitive evidence

OR

2. Laboratory suggestive evidence AND clinical evidence.

Laboratory definitive evidence

1. Detection of anti-hepatitis C antibody from a person who has had a negative anti-hepatitis C antibody test recorded within the past 24 months

OR

2. Detection of hepatitis C virus by nucleic acid testing from a person who has a negative anti-hepatitis C antibody test result currently, or has had, within the past 24 months

OR

3. Detection of anti-hepatitis C antibody from a child aged 18 months to 24 months

OR

4. Detection of hepatitis C virus by nucleic acid testing in a child aged 3 months to 24 months.

Laboratory suggestive evidence

Detection of anti-hepatitis C antibody, or hepatitis C virus by nucleic acid testing in a patient with no prior evidence of hepatitis C infection.

Clinical evidence

Clinical hepatitis within the past 24 months (where other causes of acute hepatitis have been excluded) defined as

1. Jaundice

OR

2. Bilirubin in urine

OR

3. Alanine transaminase (ALT) ten times the upper limit of normal.

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