Hepatitis B (newly acquired) case definition

This document contains the case definition for hepatitis B - newly acquired which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.

Page last updated: 01 July 2015

Version Status Last reviewed Endorsement date Implementation date
1.1

Laboratory Definitive Evidence
For clarity, remove “in the absence of prior evidence of hepatitis B infection” and insert “except where there is prior evidence of hepatitis B infection”.

Note
To caution about the influence of recent vaccination, add note:
“Transient HBsAg positivity can occur in patients following HBV vaccination.  This occurs more commonly in dialysis patients and is unlikely to persist beyond 14 days post-vaccination”

CDWG February 2015 CDNA April 2015 1 July 2015
1.0 Initial CDNA case definition (2004).      

Reporting

Only confirmed cases should be notified.

Confirmed case

A confirmed case requires laboratory definitive evidence only.

Laboratory definitive evidence

Detection of hepatitis B surface antigen (HBsAg) in a patient shown to be negative within the last 24 months

OR

Detection of HBsAg and IgM to hepatitis B core antigen, except where there is prior evidence of hepatitis B infection

OR

Detection of hepatitis B virus by nucleic acid testing, and IgM to hepatitis B core antigen, except where there is prior evidence of hepatitis B infection

Note:

Transient HBsAg positivity can occur in patients following HBV vaccination.  This occurs more commonly in dialysis patients and is unlikely to persist beyond 14 days post-vaccination.

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