Brucellosis Case Definition

This document contains the case definitions for Brucellosis which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.

Page last updated: 01 July 2016

PDF printable version of Surveillance case definition for Brucellosis (PDF 108 KB)

Surveillance case definition V1.2

Version
Status
Last reviewed
Endorsement date
Implementation date
1.2

Laboratory definitive evidence

  • Addition of “Detection of Brucella species by nucleic acid testing in a blood sample”.
  • IgG seroconversion description re-worded.
  • Removal of “agglutination and complement fixation titres”.

Laboratory suggestive evidence

Addition of “detection of Brucella species by nucleic acid testing from a sterile site other than blood”.
CDWG 8 December 2015 CDNA 2 February 2016 1 July 2016

1.1

  1. Members agreed to add a definition for probable case requiring laboratory suggestive and clinical evidence:

Probable case

A probable case requires laboratory suggestive and clinical evidence.

Laboratory suggestive evidence

A single high Brucella agglutination titre

Clinical evidence

A clinically compatible illness

  1. The words “in parallel” were added to point 2 under “Laboratory definitive evidence”.
CDWG 29 June 2010 CDNA 7 July 2010 1 July 2010
1.0 Initial CDNA case definition (2004)      

Reporting

Confirmed and probable cases should be notified.

Confirmed case

A confirmed case requires laboratory definitive evidence only.

Laboratory definitive evidence

  1. Isolation of Brucella species

OR

  1. Detection of Brucella species by nucleic acid testing from a blood sample

OR

  1. IgG seroconversion or a significant increase in IgG antibody level (e.g. fourfold or greater rise) to Brucella.

Probable case

A probable case requires laboratory suggestive and clinical evidence.

Laboratory suggestive evidence

  1. A single high agglutination titre to Brucella

OR

  1. Detection of Brucella species by nucleic acid testing from a normally sterile site other than blood.

Clinical evidence

A clinically compatible illness.


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