Brucellosis case definition - V1.1

This document contains the case definitions for Brucellosis which is nationally notifiable within Australia. This definition should be used to determine whether a case should be notified.

Page last updated: 09 August 2010

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Surveillance case definition V1.1

Version
Status
Last reviewed
Endorsement date
Implementation date

1.1

1.  Members agreed to add a definition for probable case requiring laboratory suggestive and clinical evidence:

Probable case

A probable case requires laboratory suggestive and clinical evidence.

Laboratory suggestive evidence
A single high Brucella agglutination titre

Clinical evidence
A clinically compatible illness

2.  The words “in parallel” were added to point 2 under “Laboratory definitive evidence”.

CDWG 29 June 2010 CDNA 7 July 2010 1 July 2010
1.0 Initial CDNA case definition (2004)      

Reporting

Confirmed and probable cases should be notified.

Confirmed case

A confirmed case requires laboratory definitive evidence only.

Laboratory definitive evidence

1. Isolation of Brucella species
OR
2. IgG seroconversion or a significant increase in antibody level or a fourfold or greater rise in titre in Brucella agglutination titres or complement fixation titres between acute and convalescent phase serum samples. (Where possible both tests should be conducted in parallel at the same laboratory.)

Probable case

A probable case requires laboratory suggestive and clinical evidence.

Laboratory suggestive evidence

A single high Brucella agglutination titre

Clinical evidence

A clinically compatible illness.


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